SCD_ANALYSIS_REPORT & MALARIA_PREVELANCE

Male

56

Female

145

I have SCD

92

I have SCDP family

109

Malaria Map for Children 6 to 59 Months of Age

Excited about new treatments for SCD

Future Research

Age Distribution

Genotype

Genotype	n	percentage
AA	4	1.9900498
AS	5	2.4875622
As	6	2.9850746
I'm AS and my late husband is AS	2	0.9950249
SC	14	6.9651741
SS	170	84.5771144

Future research topics related to sickle cell disease (SCD), we can explore several important areas based on the data provided:

1. Complications of SCD

Complications such as leg ulcers, stroke, and avascular necrosis (AVN) are significant challenges for individuals with SCD. Research could focus on:

Prevention Strategies: Investigating interventions to reduce the incidence of complications.
Treatment Innovations: Developing new therapies or improving existing ones to manage and mitigate these complications effectively.

2. Cures and Curative Treatments

While bone marrow transplants offer a potential cure for some individuals with severe SCD, more accessible and universally applicable curative treatments are needed. Research in this area might include:

Gene Therapy: Advancing gene editing techniques to correct the genetic mutation causing SCD.
Stem Cell Research: Exploring new approaches using stem cells for curative purposes.

3. Genetics and Inheritance of SCD

Understanding the genetic basis and inheritance patterns of SCD is crucial. Research topics could involve:

Genetic Modifiers: Identifying genetic factors that influence disease severity and progression.
Population Studies: Examining how genetic variations impact different populations and their susceptibility to SCD complications.

4. Mental Health and Psychological Effects

SCD not only affects physical health but also has profound psychological impacts. Areas for research include:

Psychosocial Interventions: Developing tailored support programs for individuals and families affected by SCD.
Quality of Life: Assessing the long-term psychological effects and quality of life outcomes in SCD patients.

5. Organ Damage

SCD can lead to progressive damage in various organs. Research directions could include:

Organ-Specific Studies: Investigating mechanisms of organ damage and potential therapeutic targets.
Early Detection: Developing biomarkers or imaging techniques for early detection and intervention.

6. Pain and Pain Management

Pain is a hallmark of SCD and significantly impacts quality of life. Research avenues might include:

Pain Mechanisms: Understanding the underlying mechanisms of pain in SCD.
Personalized Pain Management: Tailoring pain management strategies based on genetic, demographic, and clinical factors.

Age Range Distribution

Based on the provided data, age ranges of individuals affected by SCD vary widely, suggesting the need for age-specific research and interventions.

Genotype Distribution

The distribution of genotypes (SS, SC, AS, etc.) influences disease severity and outcomes, highlighting the importance of genotype-specific research and personalized medicine approaches.

By addressing these research topics comprehensively, we can advance our understanding of SCD, improve patient outcomes, and move closer to finding effective cures and management strategies for this challenging disease.

The first 10 rows of the data used in this dashboard is shown below and can be downloaded as a csv

This data comes from ‘a survey conducted to check the awareness and readiness to accept treatment of SCD’

Nigeria leads the world in the number of SCD cases. Approximately 150,000 babies are born annually with SCD in Nigeria. Sadly, 70-90% of affected infants die before reaching age 5. Nigerian SCD patients face staggering healthcare costs, with monthly expenses ranging from N70,000 to N1,000,0003. Up to 650 children die per day in sub-Saharan Africa from SCD1.{Arwa et al., 2019}

A video speaking to the what you need to know by ‘CMs’ is shown below: